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D. S. Tereshchenko, Yu. V. Skornyakov, Ye. V. Shuvalova, Ye. F. Litvinov, M. V. Proskurnina, N. S. Zefirov

A new approach to synthesis of 2,3-disubstituted g-aminobutyric acids and their derivatives

Abstract

The new synthetic approach to 2,3-substituted 4-aminobutiric acids is offered. This method comprises a selective catalytic reduction of 3-cyanopropionic esters, formed with high yields by the reaction of 2,3-substituted cyclopropenones with sodium cyanide in the presence of corresponding alcohol.
Moscow University Chemistry Bulletin.
2007, Vol. 48, No. 5, P. 317
   

Copyright (C) Chemistry Dept., Moscow State University, 2002
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