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V. P. Shevchenko, G. A. Badun, I. Yu. Nagayev, M. G. Chernyshiova, V. V. Shevchenko
Synthesis
of Tritium Labeled Compounds Using Fibroid Carbon Carrier
Abstract
The results of tritium
labeling of organic compounds by solid phase catalysis using multi-walls carbon
nanotubes were compared with one obtained by using activated carbon purchased
from “Norit”. It was found that utilization of multi-walls carbon nanotubes
lead to considerable growth of the yield (10–20 times) and molar radioactivity
(1.5–2 times) of labeled compounds. Using such carrier it became possible to
obtain tritium labeled biological active compound like diazepam, etomidat,
proline, phenylalanine with molar radioactivity 10–25 Ci/mmol
Copyright (C) Chemistry Dept., Moscow State University, 2002
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